For a complete listing of publications on PubMed, click here.

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Selected References:​

• Scott-Hewitt, N., Mahoney, M., Huang, Y., Korte, N., Soysa, T. Y. de, Wilton, D. K., Knorr, E., Mastro, K., Chang, A., Zhang, A., Melville, D., Schenone, M., Hartigan, C., & Stevens, B. (2024). Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain. Cell, 0(0). https://doi.org/10.1016/j.cell.2024.05.05 

• Baum, M. L., Wilton, D. K., Fox, R. G., Carey, A., Hsu, YH.H., Hu, R., Jäntti, HJ., Fahey, J.B., Muthukumar, A.K., Salla, N., Crotty, W., Scott-Hewitt, N., Bien, E., Sabatini, D.A., Lanser, T.B., Frouin, A., Gergits, F., Håvik, B., Gialehi, C., Nacu, E., Lage, K., Blom, A.M., Eggan, K., McCarroll, S.A., Johnson, M.B., Stevens, B. (2024). CSMD1 regulates brain complement activity and circuit development. Brain, Behavior, Immunity. 2024 Jul;119:317-332. https://doi.org/10.1016/j.bbi.2024.03.041 

• Wilton, D.K., Mastro, K., Heller, M.D. et al. Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington’s disease. Nat Med(2023). https://doi.org/10.1038/s41591-023-02566-3

• Dissing-Olesen, L., Walker, A. J., Feng, Q., Barr, H. J., Walker, A. C., Xie, L., Wilton, D. K., Das, I., Benowitz, L. I., & Stevens, B. (2023). FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins. Nature Communications, 14(1), Article 1. https://doi.org/10.1038/s41467-023-41448-7

• Gazestani, V., Kamath, T., Nadaf, N. M., Dougalis, A., Burris, S. J., Rooney, B., Junkkari, A., Vanderburg, C., Pelkonen, A., Gomez-Budia, M., Välimäki, N.-N., Rauramaa, T., Therrien, M., Koivisto, A. M., Tegtmeyer, M., Herukka, S.-K., Abdulraouf, A., Marsh, S. E., Hiltunen, M., … Macosko, E. Z. (2023). Early Alzheimer’s disease pathology in human cortex involves transient cell states. Cell, 186(20), 4438-4453.e23. https://doi.org/10.1016/j.cell.2023.08.005

• Rueda-Carrasco J, Sokolova D, Lee SE, Childs T, Jurčáková N, Crowley G, De Schepper S, Ge JZ, Lachica JI, Toomey CE, Freeman OJ, Hardy J, Barnes SJ, Lashley T, Stevens B, Chang S, Hong S. Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models. EMBO J. 2023 Aug 14:e113246. doi: 10.15252/embj.2022113246. Epub ahead of print. PMID: 37575021.

• Dolan MJ, Therrien M, Jereb S, Kamath T, Gazestani V, Atkeston T, Marsh SE, Goeva A, Lojek NM, Murphy S, White CM, Joung J, Liu B, Limone F, Eggan K, Hacohen N, Bernstein BE, Glass CK, Leinonen V, Blurton-Jones M, Zhang F, Epstein CB, Macosko EZ, Stevens B. Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro. Nat Immunology. 2023 Jul;24:1382-1390. doi: https://doi.org/10.1038/s41590-023-01558-2. Epub 2023. PMID: 37500887

• Scott-Hewitt N, Huang Y, Stevens B. Convergent mechanisms of microglia-mediated synaptic dysfunction contribute to diverse neuropathological conditions. Ann N Y Acad. Sci. 2023 Jul;1525(1):5-27. doi: 10.1111/nyas.15010. Epub 2023. PMID: 37272510. 

• Pinho-Ribiero FA, Deng L, Neel DV, Erdogan O, Basu H, Yang D, Choi S, Walker AJ, Carneiro-Nascimento S, He K, Wu G, Stevens B, Doran KS, Levy D, Chiu IM. Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion. Nature. 2023 Mar;615:472-481. doi: https://doi.org/10.1038/s41586-023-05753-x. Epub 2023.  PMID: 36859544

• Rapino F, Natoli T, Limone F, O'Connor E, Blank J, Tegtmeyer M, Chen W, Norabuena E, Narula J, Hazelbaker D, Angelini G, Barrett L, O'Neil A, Beattie UK, Thanos JM, de Rivera H, Sheridan SD, Perlis RH, McCarroll SA, Stevens B, Subramanian A, Nehme R, Rubin LL. Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes. Stem Cell Reports. 2023 Jan 10;18(1):237-253. doi: 10.1016/j.stemcr.2022.11.018. Epub 2022 Dec 22. PMID: 36563689.

• Gazestani V, Kamath T, Nadaf NM, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Rauramaa T, Therrien M, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh S, Malm T, Hiltunen M, Nehme R, Stevens B, Leinonen V, Macosko EZ. Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states. bioRxiv [Preprint]. 2023 Jun 5:2023.06.03.543569. doi: 10.1101/2023.06.03.543569. PMID: 37333365; PMCID: PMC10274680.

• Wieder N, Fried JC, Kim C, Sidhom EH, Brown MR, Marshall JL, Arevalo C, Dvela-Levitt M, Kost-Alimova M, Sieber J, Gabriel KR, Pacheco J, Clish C, Abbasi HS, Singh S, Rutter JC, Therrien M, Yoon H, Lai ZW, Baublis A, Subramanian R, Devkota R, Small J, Sreekanth V, Han M, Lim D, Carpenter AE, Flannick J, Finucane H, Haigis MC, Claussnitzer M, Sheu E, Stevens B, Wagner BK, Choudhary A, Shaw JL, Pablo JL, Greka A. FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity. Cell Metab. 2023 May 2;35(5):887-905.e11. doi: 10.1016/j.cmet.2023.03.018. Epub 2023 Apr 18. PMID: 37075753; PMCID: PMC10257950.

• Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 Nov 2;110(21):3458-3483. doi:10.1016/j.neuron.2022.10.020. PMID: 36327895.

• Marsh SE, Walker AJ, Kamath T, Dissing-Olesen L, Hammond TR, de Soysa TY, Young AMH, Murphy S, Abdulraouf A, Nadaf N, Dufort C, Walker AC, Lucca LE, Kozareva V, Vanderburg C, Hong S, Bulstrode H, Hutchinson PJ, Gaffney DJ, Hafler DA, Franklin RJM, Macosko EZ, Stevens B. Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain. Nat Neurosci. 2022 Mar;25(3):306-316. doi: 10.1038/s41593-022-01022-8. Epub 2022 Mar 8. PMID: 35260865.

• Qureshi YH, Berman DE, Marsh SE, Klein RL, Patel VM, Simoes S, Kannan S, Petsko GA, Stevens B, Small SA. The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease. Cell Rep. 2022 Jan 18;38(3):110262. doi: 10.1016/j.celrep.2021.110262. PMID: 35045281.

• Stevens B, Johnson MB. The complement cascade repurposed in the brain. Nat Rev Immunol. 2021 Oct;21(10):624-625. doi: 10.1038/s41577-021-00621-z. PMID: 34580464.

• Peterson SL, Li Y, Sun CJ, Wong KA, Leung KS, de Lima S, Hanovice NJ, Yuki K, Stevens B, Benowitz LI. Retinal Ganglion Cell Axon Regeneration Requires Complement and Myeloid Cell Activity within the Optic Nerve. J Neurosci. 2021 Oct 13;41(41):8508-8531. doi: 10.1523/JNEUROSCI.0555-21.2021. Epub 2021 Aug 20. PMID: 34417332; PMCID: PMC8513703.

• Favuzzi E, Huang S, Saldi GA, Binan L, Ibrahim LA, Fernández-Otero M, Cao Y, Zeine A, Sefah A, Zheng K, Xu Q, Khlestova E, Farhi SL, Bonneau R, Datta SR, Stevens B, Fishell G. GABA-receptive microglia selectively sculpt developing inhibitory circuits. Cell. 2021 Jul 22;184(15):4048-4063.e32. doi: 10.1016/j.cell.2021.06.018. Epub 2021 Jul 6. Erratum in: Cell. 2021 Oct 28;184(22):5686. PMID: 34233165.

• Young AMH, Kumasaka N, Calvert F, Hammond TR, Knights A, Panousis N, Park JS, Schwartzentruber J, Liu J, Kundu K, Segel M, Murphy NA, McMurran CE, Bulstrode H, Correia J, Budohoski KP, Joannides A, Guilfoyle MR, Trivedi R, Kirollos R, Morris R, Garnett MR, Timofeev I, Jalloh I, Holland K, Mannion R, Mair R, Watts C, Price SJ, Kirkpatrick PJ, Santarius T, Mountjoy E, Ghoussaini M, Soranzo N, Bayraktar OA, Stevens B, Hutchinson PJ, Franklin RJM, Gaffney DJ. A map of transcriptional heterogeneity and regulatory variation in human microglia. Nat Genet. 2021 Jun;53(6):861-868. doi: 10.1038/s41588-021-00875-2. Epub 2021 Jun 3. PMID: 34083789; PMCID: PMC7610960.

• Mifflin L, Hu Z, Dufort C, Hession CC, Walker AJ, Niu K, Zhu H, Liu N, Liu JS, Levin JZ, Stevens B, Yuan J, Zou C. A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2025102118. doi: 10.1073/pnas.2025102118. PMID: 33766915; PMCID: PMC8020785.

• Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC. Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice. Nat Neurosci. 2021 Feb;24(2):214-224. doi: 10.1038/s41593-020-00763-8. Epub 2020 Dec 22. PMID: 33353966; PMCID: PMC8086435.

• Pedersen H, Jensen RK, Jensen JMB, Fox R, Pedersen DV, Olesen HG, Hansen AG, Christiansen D, Mazarakis SMM, Lojek N, Hansen P, Gadeberg TAF, Zarantonello A, Laursen NS, Mollnes TE, Johnson MB, Stevens B, Thiel S, Andersen GR. A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity. J Immunol. 2020 Oct 15;205(8):2287-2300. doi: 10.4049/jimmunol.2000752. Epub 2020 Sep 16. PMID: 32938727.

• Cheadle L, Rivera SA, Phelps JS, Ennis KA, Stevens B, Burkly LC, Lee WA, Greenberg ME. Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism. Neuron. 2020 Nov 11;108(3):451-468.e9. doi: 10.1016/j.neuron.2020.08.002. Epub 2020 Sep 14. PMID: 32931754; PMCID: PMC7666095.

• Liddelow SA, Marsh SE, Stevens B. (2020) Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?. Trends Immunol. 2020;41(9):820-835. doi:10.1016/j.it.2020.07.006. PMID: 32819809

• Zarantonello, A., Presumey, J., Simoni, L., Yalcin, E., Fox, R., Hansen, A., Olesen, H. G., Thiel, S., Johnson, M. B., Stevens, B., Laursen, N. S., Carroll, M. C., & Andersen, G. R. (2020). An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase. The Journal of Immunology, ji2000528. https://doi.org/10.4049/jimmunol.2000528

• Wilton DK, Stevens B. (2020) The contribution of glial cells to Huntington's disease pathogenesis. Neurobiol Dis. ;143:104963. doi: 10.1016/j.nbd.2020.104963. Epub 2020 Jun 25. PMID: 32593752.

• Li T, Chiou B, Gilman CK, et al. A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding [published online ahead of print, 2020 May 25]. EMBO J. 2020;e104136. doi:10.15252/embj.2019104136

• Scott-Hewitt N, Perrucci F, Morini R, Ergeni M, Mahoney M, Witkowska A, Carey A, Faggiani E, Schuetz L, Mason S, Tamborini M, Bizzotto M, Passoni L, Filipello F, Jahn R, Stevens B, Matteoli M. (2020) Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia. EMBO e105380. 2020 July 15. doi: 10.15252/embj.2020105380

• Welsh CA, Stephany CÉ, Sapp RW, Stevens B. Ocular Dominance Plasticity in Binocular Primary Visual Cortex Does Not Require C1q. J Neurosci. 2020;40(4):769-783. doi:10.1523/JNEUROSCI.1011-19.2019

• Wallace J, Lord J, Dissing-Olesen L, Stevens B, Murthy V. (2020) Microglial depletion disrupts normal functional development of adult-born neurons in the olfactory bulb. eLife 2020;9:e50531. doi: 10.7554/eLife.50531

• Wilton DK, Dissing-Olesen  L, Stevens B. (2019) Neuron-Glia Signaling in Synapse Elimination. Annual Review of Neuroscience. 2019 July 8;42:107-127. doi: 10.1146/annurev-neuro-070918-050306.

• Hammond TR, Marsh SE, Stevens B. (2019) Immune Signaling in Neurodegeneration. Immunity. 2019 April 16;50:955-974. doi: 10.1016/j.immuni.2019.03.016.

• Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Saunders A, Macosko E, Franklin RJM, Piao X, McCarroll S, Stevens B. (2019). Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. Immunity. 2019 Jan 15. 50:253-271. doi: https://doi.org/10.1016/j.immuni.2018.11.004.

• Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B. (2018). CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron. October 10;100(1):120-134. doi: https://doi.org/10.1016/j.neuron.2018.09.017.

• Hammond TR, Robinton D, Stevens B. (2018). Microglia and the Brain: Complementary Partners in Development and Disease.  Annu Rev Cell Dev Biol. 2018 Oct 6;34:523-544. doi: 10.1146/annurev-cellbio-100616-060509. 

• Lim RG, Salazar LL, Wilton DK, King AR, Stocksdale JT, Sharifabad D, Lau AL, Stevens B, Reidling JC, Winokur ST, Casale MS, Thompson LM, Pardo M, Garcia Diaz-Barriga AG, Straccia M, Sanders P, Alberch J, Canals JM, Kaye JA, Dunlap M, Jo L, May H, Mount E, Anderson-Bergman C, Haston K, Finkbeiner S, Kedaigle AJ, Gipson TA, Yildirim F, Ng CW, Milani P, Housman DE, Fraenkel E, Allen ND, Kemp PJ, Atwal RS, Biagioli M, Gusella JF, MacDonald ME, Akimov SS, Arbez N, Stewart J, Ross CA, Mattis VB, Tom CM, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Svendsen CN. (2017) Developmental alterations in Huntington’s neural cells and pharmacological rescue in cells and mice. Nature Neuroscience. 2017 Mar 20;20:648-660. doi: 10.1038/nn.4532

• Hong S*, Wilton DK*, Stevens B, Richardson DS. (2016) Structured Illumination Microscopy for the Investigation of Synaptic Structure and Function. Methods Mol Biol. 2017;1538:155-167.

• Loh KH, Stawski PS, Draycott AS, Udeshi ND, Lehrman EK, Wilton DK, Svinkina T, Deerinck TJ, Ellisman MH, Stevens B, Carr SA, Ting AY. (2016) Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell. 2016 Aug 25;166(5):1295-1307. doi: 10.1016/j.cell.2016.07.041.

• Schafer DP, Heller CT, Gunner G, Heller M, Gordon C, Hammond T, Wolf Y, Jung S, Stevens B. (2016). Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression. Elife. 2016 Jul 26;5. pii: e15224. doi: 10.7554/eLife.15224.

• Hong S, Stevens B. (2016). Microglia: Phagocytosing to Clear, Sculpt, and Eliminate. Dev Cell. 2016 Jul 25;38(2):126-8. doi: 10.1016/j.devcel.2016.07.006.

• Vasek MJ, Garber C, Dorsey D, Durrant DM, Bollman B, Soung A, Yu J, Perez-Torres C, Frouin A, Wilton DK, Funk K, DeMasters BK, Jiang X, Bowen JR, Mennerick S, Robinson JK, Garbow JR, Tyler KL, Suthar MS, Schmidt RE, Stevens B, Klein RS. (2016). A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016 Jun 22;534(7608):538-43. doi: 10.1038/nature18283.

• Hong S, Beja-Glasser VF, Nfonoyim BM, Frouin A, Li S, Ramakrishnan S, Merry KM, Shi Q, Rosenthal A, Barres BA, Lemere CA, Selkoe DJ, Stevens B. (2016). Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science. 2016 May 6;352(6286):712-6. doi: 10.1126/science.aad8373.

• Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; Schizophrenia Working Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC, Stevens B, McCarroll SA. (2016). Schizophrenia risk from complex variation of complement component 4. Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038/nature16549.

• Chung WS, Welsh CA, Barres BA, Stevens B. (2015). Do glia drive synaptic and cognitive impairment in disease? Nat Neurosci. 2015 Nov;18(11):1539-45. doi: 10.1038/nn.4142.

• Wu Y, Dissing-Olesen L, MacVicar BA, Stevens B. (2015). Microglia: Dynamic Mediators of Synapse Development and Plasticity. Trends Immunol. 2015 Oct;36(10):605-13. doi: 10.1016/j.it.2015.08.008.

• Dissing-Olesen L, Hong S, Stevens B. (2015). New Brain Lymphatic Vessels Drain Old Concepts. EBioMedicine. 2015 Aug 14;2(8):776-7. doi:10.1016/j.ebiom.2015.08.019. eCollection 2015 Aug.

• Shi Q, Colodner KJ, Matousek SB, Merry K, Hong S, Kenison JE, Frost JL, Le KX, Li S, Dodart JC, Caldarone BJ, Stevens B, Lemere CA. (2015). Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline. J Neurosci. 2015 Sep 23;35(38):13029-42. doi: 10.1523/JNEUROSCI.1698-15.2015.

• Schafer DP, Stevens B. (2015). Microglia Function in Central Nervous System Development and Plasticity. Cold Spring Harb Perspect Biol. 2015 Jul 17;7(10). pii: a020545. doi: 10.1101/cshperspect.a020545.

• Lehrman EK, Stevens B. (2015). Shedding light on glioma growth. Cell. 2015 May 7;161(4):704-6. doi: 10.1016/j.cell.2015.04.036.

• Schafer DP, Stevens B. (2015). Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages. Immunity. 2015 Apr 21;42(4):600-2. doi: 10.1016/j.immuni.2015.04.002.

• Giera S, Deng Y, Luo R, Ackerman SD, Mogha A, Monk KR, Ying Y, Jeong SJ, Makinodan M, Bialas AR, Chang BS, Stevens B, Corfas G, Piao X. (2015). The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development. Nat Commun. 2015 Jan 21;6:6121. doi: 10.1038/ncomms7121.

• Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz LJ, Singh Alvarado J, Calhan OY, Silver DL, Stevens B, Calakos N, Soderling SH, Eroglu C. (2014). Astrocytes refine cortical connectivity at dendritic spines. Elife. 2014 Dec 17;3. doi: 10.7554/eLife.04047.

• Bilimoria PM, Stevens B (2014). Microglia function during brain development: New insights from animal models. Brain Research. Nov 26. pii: S0006-8993(14)01616-3. doi: 10.1016/j.brainres.2014.11.032

• Schafer DP, Lehrman EK, Heller CT, Stevens B (2014). An engulfment assay: a protocol to assess interactions between CNS phagocytes and neurons. Journal of Visual Experiments. Jun 8; (88). doi: 10.3791/51482.

• Wu LJ, Stevens B, Duan S, MacVicar BA (2013). Microglia in neuronal circuits. Neural Plasticity. 2013;2013:586426. doi: 10.1155/2013/586426.

• Schafer DP, Lehrman EK, Kautzman AG, Koyama, R, Mardinly AR, Greenberg ME, Barres BA, and Stevens, B (2012). Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement Dependent Manner. Neuron,74; 1-15.

• Ransohoff RM, Stevens B. (2011). How Many Cell Types Does It Take to Wire a Brain? Science 333: 1391-92

• Stephan, AH, Barres BA and Stevens, B (2012) The complement system: an unexpected role in synaptic pruning during development and disease. Annual Reviews Neuroscience (in press).

• Tremblay M, Stevens B, et al. (2011). The Role of Microglia in the Healthy Brain. J. Neuroscience 31(45):16064-9.

• Schafer DP, Lehrman E and Stevens B. (2012). “Quad-partite” Synapse: Microglia-Synapse Interactions in the Developing and Mature CNS. Glia (Special Issue on Microglia) (in press)

• Rosen, AM and Stevens, B (2012) Glia and Immune Molecules in Visual Development. The New Visual Neuroscience (Editors: Leo Chalupa; McAllister Kimberly; Barbara Chapman, MIT Press) (In press).

• Blank M, Feust PG, Stevens B, Nouri, N, Kirkby L, Warrier D, Barres BA, Feller MB, Huberman AD, Burgess RW, Garner, CC (2011). The Down Syndrome Critical Region Regulates Retinogeniculate Refinement. J Neuroscience31(15):5764.

• Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T,. Andreassen OA, Cichon S and Steen VM (2011). The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia. Biological Psychiatry 70(1):35-42.

• Howell GR, Macalinao DG,. Sousa GL, Soto I, Kneeland SJ, Barbay J, King BL, Marchant JK, Hibbs M , Stevens B, Barres BA , Clark AF, LibbyRT, and John SWM (2011). Molecular clustering identified complement and endothelin induction as early events in a mouse glaucoma. The Journal of Clinical Investigation 121(4):1429-44.

• Ji X, Chu Y, Parada I, Stevens B, Barres BA and Prince C (2010). Enhanced synaptic connectivity and epilepsy in C1q knockout mice. Proceedings of the National Academy of Sciences 107 (17) 7975-80.

• Rosen AM, Stevens B. (2010). The role of the classical complement cascade in synapse loss during development and glaucoma. Adv Exp Med Biology 703:75-93. Review.

• Stevens B, Allen NJ, Christopherson KS, Vazquez LE, Nouri N, Howell GR, Micheva KD, Huberman AD, Stafford B, Sher A, Litke, AM, Lambris, JD, Smith SJ, John, SWM, Barres, BA (2007). The classical complement cascade mediates developmental CNS synapse elimination. Cell 131:1164-78.

• Chen, Y, Stevens B, Chang J, Milbrandt J, Bares BA, Hell JW (2008) NS21: re-defined and modified supplement B27 for neuronal cultures. J Neuroscience Methods 171: 239-47.

• Ishabashi T, Dakin KA, Stevens B, Lee PR, Kozlov SV, Stewart CL, Fields RD (2006). Astrocytes promote myelination in response to electrical impulses. Neuron 49(6):823-32.

• Stevens B, Ishabashi T, Chen, JF and Fields RD (2004). Adenosine: an activity-dependent axonal signal regulating MAP kinase and proliferation in developing Schwann cells. Neuron Glia Biology 1: 23-34.

• Stevens B (2003). Glia: much more than the neuron’s side-kick. Curr. Biology 13:R469-472.

• Stevens B, Porta S, Haak LL, Gallo, V, and Fields RD (2002). Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials. Neuron 36:855-868.

• Stevens B and Fields RD (2000). Response of Schwann cells to action potentials in development. Science 287: 2267-2271.

• Fields RD and Stevens-Graham B (2002). New insights into neuron-glia communication. Science 298:556-562.