Nicole Scott-Hewitt

nsh-picI completed my graduate studies at the University of Rochester under the mentorship of Dr. Mark Noble, focusing on understanding the molecular mechanisms underlying lysosomal dysfunction in a group of rare genetic diseases known as Lysosomal Storage Disorders. As a postdoctoral fellow in the Stevens lab, I have several areas of research I am interested in pursing. I want to better understand mechanisms of complement-mediated synapse elimination during development and disease, through the identification of potential complement-binding proteins. I am also interested in studying how the regulation of lysosomal function may contribute to microglial phagocytosis necessary for synapse elimination, and how this may be affected in neurodegenerative disorders.