I earned my PhD in Biochemistry at the University of Milan (Italy) where I investigated the role of the glyco-sphingolipid GM1 in neuronal maturation and survival, producing insights with translational potential for Parkinsonism treatments. My deep commitment to neuroscience research, particularly in translating basic science discoveries into applied strategies for new therapeutics in neurodegenerative diseases, led me the USA where I joined the Isacson Lab at McLean Hospital (HMS) in 2021. There, my research focused on the function of APOE in neuron-glia communication, utilizing human iPSC-derived neurons, astrocytes, microglia, and mouse models to examine the effects of aging, APOE genotypes, and lipid dysregulation on inflammation and neuronal degeneration. I am particularly interested in how disruptions in lipid metabolism and trafficking contribute to the breakdown of neuron-glia interactions in neurodegenerative diseases, and how genetic predispositions, environmental exposures, and aging precipitate metabolic and lipid trafficking defects that impact glial function and neuronal health. In 2024 I joined the Stevens Lab, where I am excited to explore the broader role of immunity and inflammation, especially as it pertains to microglia in aging and neurodegeneration.
In my free time I enjoy listening to music, attending concerts, and relaxing at home watching movies.